05) more effective at inhibiting lipid oxidation than GSH over a 7-day period. In contrast, with the exception of H(2)O(2) scavenging, GSH was a more effective antioxidant than PPH and the peptide fractions. We concluded that the PPH and some of its fractions have the potential to be used as therapeutic agents against chronic diseases AZD4547 inhibitor that develop from oxidative
damage, and that the cationic property of amino acids contributed negatively to the antioxidant activity of the peptide fractions. (C) 2011 Elsevier Ltd. All rights reserved.”
“Parkinson’s disease (PD) is a neurodegenerative disorder, caused by reduced levels of catecholamines and oxidative stress. Symptoms seen in the disease include tremor, rigidity, bradykinesia and postural disability. Oxidative stress plays a key role in neurodegeneration and motor SB202190 order abnormalities seen in
PD. Altered levels of the protein caused by these changes lead to defective ubiquitin-proteasonne pathway. Neurodegeneration seen in PD and Canavan disease has a common mechanism. Recent studies suggest that herbal medicines can improve molecular changes and motor functions seen in PD.”
“Canola proteins were sequentially extracted from four Australian canola meals of different species and two industrial meal samples, according to Osborne method (OSB), based on their solubilities in water, 5% NaCl. 0.1 M NaOH and 70% ethanol respectively. These extracts were then compared to the glutelin fraction obtained by direct alkaline extraction method (DIR) in terms of protein yield, recovery, electrophoretic profile, and residual antinutritional components. The OSB method was found to be more effective for protein extraction which
resulted in higher cumulative protein yield and recovery of water-soluble protein fractions, although the DIR method produced a glutelin fraction of higher protein content. Phenolic compounds were observed in all the extracted protein Selleck Emricasan fractions although sinapine, the major phenolic compound in canola, was present only in the albumin fractions. The glucosinolate content of all extracts was below the detection limit of the method employed (<3 mu mol/g). While the electrophoretic profiles of all four OSB fractions were largely different, the DIR fraction was very similar to the glutelins obtained from the OSB method. Isoelectric focusing revealed that many of the proteins in the canola varieties ranged in pl between pH4.6 and 8.3. (C) 2011 Elsevier Ltd. All rights reserved.”
“Proprioceptive tendon reflexes are traditionally regarded as tendon stretch reflexes. Eliciting reflexes with a sharp blow on a tendon is, however, not a physiological stimulus. Based on clinical experience in eliciting these reflexes and neurophysiological investigations it is suggested that vibration is a relevant stimulus for tendon jerks.