We found certain evidence about the adverse effect of using insecticide sprays during pregnancy on the psychomotor development of children. Some socio-demographic factors and other exposures could enhance that effect. (C) 2013 Elsevier Ltd. All rights reserved.”
“Ba(Fe0.5Mn0.5)O3-delta (BFMO) single crystalline films with various amounts of the oxygen deficiencies on SrTiO3(001) substrates have been successfully synthesized WH-4-023 clinical trial by a pulsed laser deposition method. The lattice constant of the films significantly decreased with an increase in the oxygen partial pressure during the deposition process. This suggests that the radius of the Fe and Mn ions that is strongly correlated with
their Selleck HSP990 valence state systematically changed. In addition, the oxygen partial pressure has a considerable influence on the magnetic properties of the films: the saturation magnetization of the samples increased with increasing oxygen partial pressure, i.e., with decrease in the amount of the oxygen
deficiencies. The maximum saturation magnetization of 43 emu/cc for the epitaxial BFMO films was obtained at 300 K. The results of the x-ray photoelectron spectroscopic analysis revealed that the relative amount of the Fe3+ (3d(5)) and Mn4+ (3d(3)) ions increased with decreasing amount of the oxygen deficiency. This may increase the amount of the Fe3+(3d(5))-O2–Mn4+(3d(3)) ferromagnetic superexchange coupling with 180 degrees bonding angle, which selleck compound led to the ferromagnetic spin alignment in the samples. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3062950]“
“Background: Peritoneal fibrosis is an essential precursor condition to the development of encapsulating peritoneal sclerosis (EPS). This serious complication leads to a high mortality rate in peritoneal dialysis (PD) patients. Although several factors, including highly concentrated glucose in the dialysis solution, are believed to be potent agents for peritoneal fibrosis, the underlying mechanism
remains unclear. During PD, the dialysis solution continuously generates fluid flow stress to the peritoneum under peristalsis and body motion. Fluid flow stress has been implicated as playing a critical role in the physiologic responses of many cell types. We therefore hypothesized that fluid flow stress may be involved in the pathogenesis of peritoneal fibrosis leading to EPS.
Methods: To generate fluid flow stress, culture containers were placed on a rotatory shaker in a thermostatic chamber. In this system, the shaker rotated at a speed of 25 rpm with a radius of 1.5 cm. Mesothelial cells were cultured in low-glucose (1000 mg/L) or high-glucose (4500 mg/L) complete medium with and without flow stress.
Results: Fluid flow stress promoted hyperplasia and epithelial-mesenchymal transition (EMT) of mesothelial cells independent of glucose concentration.