Methods. In the study, 64-slice CT was used to evaluate 36 patients who had undergone coronary 17DMAG mw artery bypass graft surgery and had a clinical indication for angiographic graft assessment. The diagnostic accuracy of CT for identifying significant lesions in grafts and native coronary arteries was determined and compared with that of invasive

coronary angiography.

Results. Of the 103 grafts studied (49 arterial and 54 venous), 96 (93.2%) could be visualized by angiography and 98 (95.1%) by CT. The sensitivity and specificity of CT for detecting significant lesions in grafts were 100% (30/30) and 97% (64/66), respectively, and the positive predictive value (PPV) and negative predictive value (NPV) were 94% and 100%, respectively. For non-revascularized coronary arteries (258 segments), the sensitivity, specificity, PPV and NPV were 94%, 95%, 80% and 99%,

respectively, and for distal vessels, 86%, 97%, 67% and 99%, respectively.

Conclusions. The diagnostic accuracy of 64-slice CT for evaluating both coronary grafts and native coronary arteries was high.”
“Case Description-A 7-year-old Quarter Horse gelding used for unsanctioned racing was examined because of fever and anorexia.

Clinical Findings-Physical examination revealed fever, tachycardia, and tachypnea. Results of a CBC indicated anemia and mild thrombocytopenia. PP2 cost Results of microscopic examination of a blood smear indicated piroplasms in erythrocytes, consistent with Babesia spp. Regulatory authorities Selleckchem CH5183284 were contacted, and results of serologic testing at the National Veterinary Services Laboratories confirmed acute Babesia equi infection.

Treatment and Outcome-Equids on the home premises of the index horse were placed

under quarantine. Those equids were tested for piroplasmosis, and 6 of 63 horses had positive results for B equi. Another horse that had previously been housed on the index premises also had positive results for B equi. Competent tick vectors for piroplasmosis organisms were not identified. All 8 horses with piroplasmosis were Quarter Horses that participated in unsanctioned racing and were trained by the same person. Two of the horses were illegally removed from the index premises; these 2 horses and the other horse with piroplasmosis that was previously housed on the index premises could not be found. The other 5 horses with piroplasmosis were euthanized. Investigators concluded that transmission of B equi among horses was most likely iatrogenic.

Relevance-The United States has been considered piroplasmosis free. However, veterinarians should consider piroplasmosis in horses with signalments and clinical signs similar to those of the index horse of this report. Regulatory authorities should be contacted regarding horses in which piroplasmosis is suspected. (J Am Vet Med Assoc 2013;242:992-996)”
“Background: Folic acid can prevent up to 70% of neural tube defects (NTDs) if taken before pregnancy.