Out of 384 individuals, 236 customers (61.5%) had NAFLD on ultrasound. Clients with NAFLD had higher mean BMI, higher HbA1c, increased waistline circumference, raised ALT, higher triglyceride, and reasonable HDL. Logistic regression analysis revealed a statistically significant relationship with central obesity (OR = 5.448, 95% CI = 1.416-20.959, p = 0.014), higher BMI (OR = 4.435, 95% CI = 2.127-9.246, p < 0.0001), higher HbA1c [> 11%] (OR = 3.602, 95% CI = 1.438-9.019, p = 0.006), and elevated ALT (OR = 3.211, 95% CI = 1.509-6.835, p = 0.002). The best chances for NAFLD had been found for hypertriglyceridemia (OR = 11.624, 95% CI = 5.405-24.998, p < 0.0001) and low HDL (OR = 11.543, 95% CI = 2.590-51.439, p = 0.001), correspondingly. High-frequency of NAFLD along with its connected clinical and laboratory danger factors had been revealed. This underpins the significance of testing T2DM patients for NAFLD and assessment for and customization of their linked risk facets in routine medical rehearse.High-frequency of NAFLD along side its associated medical and laboratory risk facets had been uncovered. This underpins the significance of screening T2DM patients for NAFLD and assessment for and adjustment of its linked risk facets in routine medical training. Vincristine has been utilized as chemotherapeutic representative for a lot of years. It implements its function by inhibiting the duplication of cyst cells by destroying the DNA. However, like all various other medications, its management just isn’t with no side effects. The most crucial of the are increasingly being the neurotoxic negative effects. This study evaluated the amount of neurotoxicity induced by vincristine in kids which underwent chemotherapy for severe lymphoblastic leukemia and Wilms cyst. a quasi-experimental research ended up being conducted at Children Hospital & the Institute of Child Health, Multan from January 2020 to October 2020 after taking informed penned consent. In this research, 150 kiddies of age group 1 – 12 years with pathological verification of intense lymphoblastic leukemia and Wilms tumefaction who had undergone a chemotherapy protocol including at the least four consecutive regular Vincristine shots had been included, using probability consecutive sampling strategy. Neurologic evaluation was conducted on them on weekly basis. There have been 150 patients,90(60%) males and 60(40%) females with mean chronilogical age of (5.5±2.2). Diminished patellar and posterior muscle group reflexes were seen in 48% and 52% of patients. Muscular weakness ended up being noticed in 60% of customers. Other side effects like hoarseness, jaw pain, constipation and petosis had been seen in 10%, 8%,40% and 10% of customers correspondingly. Frequency of complications was similarly observed in both sexes and it learn more was more among generation over the age of five years (p= 0.01). Vincristine program produces some neurotoxic complications in children but the majority of of those are of mild to moderate in the wild.Vincristine regime produces some neurotoxic side-effects in kids but almost all of those are of mild to moderate in the wild. Out of 233, 91.41percent were grownups and 8.58% had been children (P<0.001), 66.10% had been male and 33.90% were female (P<0.001). In 55.36per cent, HN was in Hardware infection the proper kidney and 44.64% was at the left (P=0.116). Precisely 58% of patients were suffering from grade-2, 21.5% grade-3, 11.6% grade-1, and 8.2% grade-4 HN. US imaging can figure out the cause of HN in 70.4% of clients. Kidney or ureteric calculi had been the explanation for HN in 54.1percent of instances, reflux was at 7.3%, and pelviureteric junction (PUJ) stenosis was at 3.9%.In situations of calculi induced HN, 25.3percent regarding the calculi were into the vesicoureteric (VUJ) junction, 21.5% were within the renal pelvis, 6.4% had been in the PUJ or upper ureter, and only 0.9% had been in the centre ureter. Ultrasound imaging can determine the explanation for HN much more than two-thirds of patients. Calculi will be the most common cause of HN even yet in children and they are most typical into the VUJ junction.Ultrasound imaging can figure out the cause of HN in more than two thirds of patients. Calculi are the most frequent cause of HN even in young ones and generally are most common when you look at the VUJ junction. To gauge the ability and perceptions regarding Telemedicine additionally the identified barriers among health professionals. This cross-sectional survey was carried out by enrolling practicing medical practioners of Pakistan with knowledge of ≥6 months by giving a validated and piloted questionnaire through e-mail. Information collection ended up being done from 10 Two-hundred-forty responses were received with an answer rate of 63%. Female participants (62.8%) were in majority and a lot of of the members had been doing work in urban (88.5%) or semi-urban (9%) locality either in teaching (35.9%) or tertiary attention intensive lifestyle medicine hospitals (34.6%). Seventy-three per cent of the medical practioners don’t obtain formal training with over 1 / 2 of the physicians stating non-availability of infrastructure and particular equipment. Most the individuals were worried about the non-availability of regulatory figures, evaluations and aplementing tele-health. Top-notch evidence based studies are expected for practical and lasting policies.