Blood samples were obtained in the first hour of presentation for measurement of BNP levels from all patients. Detailed transthoracic
two-dimensional, Doppler and tissue Doppler echocardiographic studies were then performed within 24 hours of presentation. Statistical analyses were performed using Student’s t-test for independent samples, Mann Whitney U test and Pearson or Spearman correlation tests.\n\nResults: Plasma BNP levels were found to be significantly correlated with left ventricular end-systolic and end-diastolic diameter, left atrial diameter and the degree of mitral insufficiency signaling pathway (r=0.46, p=0.007; r=0.39, p=0.02; r=0.32, p=0.065; r=0.50, p=0.014, respectively). A significant inverse correlation was observed between plasma BNP levels and left ventricular ejection fraction (r=-0.5, p=0.003). When the patients were grouped according to their BNP levels, the mean ejection fraction of the group with BNP levels below median (578 pg/l) was 60.65 +/- 13.84%, whereas the mean ejection fraction of the group with BNP levels of 578 pg/l or above (BNP 2) was 49.41 +/-
15.26% (p=0.027). Out of parameters reflecting left ventricular diastolic functions, only transmitral Epeak/Apeak ratio was found to be significantly associated with BNP levels (r=0.4, p=0.05). Tissue Doppler study revealed significant correlations between BNP levels and right ventricular GSK1904529A molecular weight basal and midsystolic velocities (r=-0.507, p=0.008; r=-0.562, p=0.005, respectively) while none of the left ventricular tissue velocities displayed significant correlation with BNP values.\n\nConclusion: Plasma BNP levels are found to be significantly associated with conventional echocardiographic parameters reflecting left ventricular systolic and diastolic functions and tissue Doppler velocities reflecting right ventricular functions. Our findings are in agreement with the notion that plasma BNP levels are beneficial in the differential diagnosis of patients admitted to emergency service with acute
dyspnea. (Anadolu Kardiyol Berg 2010; 10: 143-9)”
“A novel controllable hybrid-anode AlGaN/GaN Tariquidar datasheet field-effect rectifier (HA-FER) with low operation voltage (LOV) is proposed. Its mechanism can be explained by the field-controlled energy band model. This model reveals that the electric field in the AlGaN layer alters the energy band to result in a variation of the two-dimensional electron gas (2DEG) at AlGaN/GaN interface; the field can be changed by the thickness.. of the AlGaN layer and the applied bias. As the.. reduces below the critical thickness, the 2DEG vanishes and then the channel is pinched off. Therefore, the threshold voltage of HA-FER can be designed as low as 0V leading to LOV (<1V). The analytical characteristic of the HA-FER is calculated and validated by the simulated results.