Besides being high in MUFA, a Mediterranean diet also contains abundant plant foods, moderate wine and low amounts of meat and dairy products, which may also play a role. We compared the effects of a high MUFA-diet with a diet high in saturated fatty acids (SFA) and the additional effect of a Mediterranean diet on insulin sensitivity and serum lipids.

Methods and results: A randomized parallel controlled-feeding Navitoclax solubility dmso trial was performed, in 60 non-diabetics (40-65 y) with mild abdominal obesity. After a two week run-in diet high in SFA (19

energy-%), subjects were allocated to a high MUFA-diet (20 energy-%), a Mediterranean diet (MUFA 21 energy-%), or the high SFA-diet, for eight weeks. The high MUFA and the Mediterranean diet did not affect fasting insulin concentrations. The high MUFA-diet reduced total cholesterol (-0.41

mmol/L, 95% CI -0.74, -0.09) and LDL-cholesterol (-0.38 mmol/L, 95% CI -0.65, -0.11) compared with the high SEA-diet, but not triglyceride concentrations. The Mediterranean diet increased HDL-cholesterol concentrations (+0.09 mmol/L, 95% CI 0.0, 0.18) and reduced the ratio of total cholesterol/HDL-cholesterol (-0.39, 95% CI -0.62, -0.16) compared with the high MUFA-diet.

Conclusion: Replacing a high SEA-diet with a high MUFA CX-5461 selleck kinase 抑制剂 or a Mediterranean diet did not affect insulin sensitivity, but improved serum lipids. The Mediterranean diet was most effective, it reduced total and LDL-cholesterol, and also increased HDL-cholesterol and reduced total cholesterol/HDL-cholesterol ratio. (C) 2009 Elsevier B.V. All rights reserved.”
“Evaluation of: Toledo-Arana A, Dussurget O, Nikitas G et al.: The Listeria transcriptional

landscape from saprophytism to virulence. Nature 459 (7249), 950-956 (2009). Bacteria adapt to a variety of environmental conditions through changes in gene regulation and gene expression. Listeria, monocytogenes is an environmental bacterium that exists as a saprophyte but is capable of transitioning into a pathogen upon ingestion by a susceptible host. In this report, Toledo-Arana et al. present the complete transcriptome of L. monocytogenes and identify a number of novel RNA regulatory elements that may facilitate bacterial adaptation to diverse environments. Their report illustrates a global coordination of transcriptional responses that takes place as the bacterium transitions from life in broth culture to life inside of an infected host.”
“Interfacial and optical properties of HfTiO films with different Ti concentration grown by radio frequency reactive magnetron sputtering have been investigated by x-ray photoelectron spectroscopy (XPS) and spectroscopy ellipsometry (SE).