95–1.12) 0.90 (0.76–1.06) 0.90 (0.79–1.04) 0.94 (0.65–1.34) 1.09 (0.98–1.22) 0.87 (0.70–1.07) Repetitive work 1.01 (0.93–1.10) 1.08 (0.91–1.28) 0.96 (0.84–1.10) 1.19 (0.83–1.69) 1.03 (0.93–1.15) 1.05 (0.85–1.30) Educational opportunities 0.96 (0.89–1.04) 0.94 (0.80–1.10) 0.95 (0.81–1.10) Selleckchem TGFbeta inhibitor 0.98 (0.68–1.42) 0.97 (0.88–1.06) 0.93 (0.77–1.12)

Job autonomya 1.03 (0.96–1.11) 0.97 (0.85–1.11) 1.07 (0.94–1.21) 0.96 (0.69–1.34) 1.00 (0.92–1.09) 1.01 (0.86–1.18) Decision authoritya 1.01 (0.92–1.10) 1.18 (0.98–1.42)# 1.04 (0.90–1.22) 1.23 (0.81–1.88) 1.02 (0.90–1.14) 1.10 (0.89–1.37) Supervisor supporta 1.05 (0.95–1.16) 0.97 (0.79–1.18) 0.91 (0.74–1.12) 1.08 (0.64–1.81) 1.08 (0.95–1.24) 0.98 (0.77–1.23) Co-worker supporta 1.09 (0.97–1.21) 1.21 (0.96–1.51) 1.13 (0.93–1.38) 1.23 (0.79–2.07) 1.12 (0.99–1.26) 1.14 (0.87–1.50) Role clarity 0.92 (0.84–1.01)# 0.87 (0.73–1.05) 0.99 (0.86–1.14) 0.82 (0.54–1.27) 0.86 (0.76–0.97)* 0.88 (0.70–1.09) Role conflict 0.99 (0.88–1.10) 0.83 (0.66–1.05) 1.04 (0.87–1.25) 1.08 (0.65–1.79) 0.95 (0.82–1.09) 0.79 (0.59–1.06) Job insecurity 1.00 (0.96–1.04) 0.96 (0.88–1.04) 0.95 (0.89–1.02) 0.90 (0.75–1.08) 1.03 (0.98–1.08) 0.95 (0.86–1.04) aReversed scales, meaning that high scale scores represent low levels of the work condition # P < 0.10, * P < 0.05 The table presents the rate ratios (RR), adjusted buy Captisol for earlier

sick-leave and psychological distress, and their 95% confidence intervals (95% CI) for the associations between the total number of sickness absence episodes, short (1–21 days) sickness absence episodes and long (>21 days) Sodium butyrate sickness absence episodes. However, the associations between

these work RG7420 clinical trial conditions and the number of sickness absence episodes were not statistically significant (Table 3). In women, the work pace (RR = 0.89, P = 0.02) and role clarity (RR = 0.86, P = 0.01) were negatively related to the number of short episodes of sickness absence. When long episodes were considered, the highest RR was found for emotional demands and co-worker support, but these associations were not significant. Discussion In this study, we prospectively analyzed associations of a wide range of psychosocial work conditions in a medium-sized insurance company with the number of registered sickness absence days and episodes in both genders, adjusting for earlier sick-leave and psychological distress, the latter being regarded as a proxy for the mental health status.