Non-menstrual pelvic pain (36%), menstrual pain (24%), constipation/diarrhea (18%), feeling sick/nauseated (14%), painful urination (9%) and irregular menstruation (7%) were the other symptoms respectively. Table 1 shows descriptive statistics of the

core and modular part of EHP-30. Table 1 Descriptive statistics of eleven dimensions of the endometriosis health profile-30 core and modular questionnaires A factor analysis with a maximum five-factor solution developed Inhibitors,research,lifescience,medical (table 2). All items were loaded on their hypothesized factor except items 17 (felt aggressive or PXD101 cell line violent) and 18 (feeling unwell) which were loaded on other factors (pain: 0.524, and social support: 0.568 domains, respectively). Table 2 Factor analysis: factor load for core domain of EHP-30 questionnaire Cronbach’s α ranged between 0.80-0.93 for core domains Inhibitors,research,lifescience,medical and 0.78-0.90 for modular domains. Table 3 and ​and44 shows corrected item to total correlation and scale internal reliability consistency (Cronbach’s α) on the EHP-30 for core and modular domains, respectively. The EHP-30 item to total correlations exceeded the margin of 0.40 in all instances for core and modular parts. Table 3 Corrected item to total correlation and scale internal reliability consistency on the EHP-30 (core questionnaire) Table 4 Corrected item to total correlation and scale internal reliability

Inhibitors,research,lifescience,medical consistency on the EHP-30 Inhibitors,research,lifescience,medical (modular questionnaire) Higher order factor analysis was undertaken on the five dimension of the EHP-30. The analysis

produced a single component, which accounted for 65.67 % of the variance that indicated the dimensions can be summed up to create a single index (the EHP-30 summary index) score (table 5). Table 5 Principal component matrix from a higher order factor analysis of the five dimensions of the EHP-30 We administered SF-36 to assess construct validity of the EHP-30. The most powerful correlation was between emotional scale of EHP-30 and emotional well-being of SF-36 (-0.63). All correlations Inhibitors,research,lifescience,medical were significant at 0.01 levels (table 6). Table 6 Correlations of endometriosis health profile-30 scales with short form-36 scales Discussion Endometriosis is Dichloromethane dehalogenase a chronic gynecological disease caused by ectopic location of the endometrium outside the uterine cavity. Because of pathological changes, and gynecological and psychiatric problems, the decline of quality of life of women with endometriosis is observed.11 Endometriosis Health profile-30 is a recently designed instrument to assess the quality of life in women with endometriosis. In this study the psychometric evaluation of Persian version of EHP-30, as a disease-specific instrument, was assessed. Internal consistency, descriptive statistics of data, factor analysis, item total correlation (corrected for overlap) and construct validity were the five criteria to assess psychometric properties of this questionnaire.