One is to focus on the blended Trichostatin A solubility working conditions, trying to find rules on how to adjust the engine’s throttle angle to get high fuel economy. Finally, to develop real-time application for PHHE that would become available. The other one is to use the optimal control results as guidance to revise rule-based control strategy accordingly.AcknowledgmentThe authors received the financial support of the National Natural Science Foundation (51205368) and the Natural Science Foundation of Zhejiang Province (Grant no. LQ12E05003).
The gap between the production of research evidence and implementation into routine clinical practice has been well acknowledged and has been referred to as the second translational gap; the first gap is that between laboratory science and clinical research [1].

With increasing recognition of the importance of not only carrying out research but also of ensuring that research findings are taken up and used by those making health care policy and providing health care, researchers and research funders are now paying more attention to dissemination, particularly active forms which have the ability to influence care delivery, and also to capturing the impact of research [2�C4].In the field of emergency care, research evidence to underpin care has been criticised both for its scarcity and quality [5]. In the prehospital setting these concerns are even more acute [6�C8]. Emergency prehospital care is a field without a strong academic tradition, but patient volume is high and outcomes are linked to responses provided by emergency medical systems (EMS).

In this growing field, demonstrating impact in practice is fundamental to the continued attraction of research funding, building of research skills and culture, and thus a high-quality evidence based to inform future policy and practice.With sustained increases in demand for emergency prehospital care across the developed world, current systems are unable to maintain services that traditionally respond to all emergency calls to the ambulance service with a paramedic staffed patient carrying vehicle travelling on lights and sirens, and with a default of conveyance to an emergency department (ED) for medical care unless the patient refused to travel. Researches focussing on the needs and outcomes of patients for whom emergency (999) calls to the ambulance service are made have shown that a substantial proportion of these patients (up to 52%) [11, 12, 15, 28] do not need immediate medical care, but that triage systems at the despatch centre and on scene that identify patients for self- or community-based care carry significant safety risks [15�C17, 22]. Unnecessary transportation Drug_discovery can also be an issue for patients who have little or no chance of survival [29].