The idea of avoidable mortality makes it possible to assess healthcare reserves and to identify priorities of these enhancement at the regional level. It was set up that into the Republic of Buryatia during 2005-2019, the percentage for the very first group because of the degrees of prevention of factors behind death of the old record (Preventable) reduced by 6.1%, mainly due to injuries, poisoning and other consequences of outside elements. The percentage of the 2nd and 3rd groups increased by 4.4per cent and 1.7%, respectively. The cause of increasing of preventable mortality tend to be malignant neoplasms and diseases of respiratory system. The rise of death from cancerous neoplasms made from11.4% for example. from 166.3 (2005) as much as 185.3 (2019) per 100 thousand of population due to increasing of death of cancerous neoplasms included in the first team (cancerous neoplasms of lip, mouth, pharynx, esophagus, liver, intrahepatic bile ducts, larynx, trachea, bronchi, lungs, urinary kidney). The growing of death from malignant neoplasms in the second team happened due to malignant neoplasms of epidermis, including melanoma, breast, cervix, womb. In this instance, the lateness of seeking medical care, which can be characteristic of a big element of populace is usually to be considered. The dynamics of percentage of respiratory conditions when you look at the framework of the third group had been described as wave-like bend, with minimal in 2008 (45.3%), and maximum in 2014 (65.1%). On top of that, total mortality of breathing diseases reduced from 84.9 to 54.6 per 100 thousand of populace. Taking into account the results for the research, it is Analytical Equipment proper to upgrade present regional preventive programs with focus on increasing diagnostic of cancerous neoplasms and appropriateness of regular preventive examinations of populace of this Republic.the goal of the analysis would be to figure out prospective availability of anti-retrovirus therapy also to justify proposals for picking and recommending rational combining of anti-retrovirus medicines for HIV therapy. The items of the study had been anti-retrovirus medicines authorized into the Russian Federation, information on present nationwide and intercontinental methods and suggestions regarding management of HIV-infected patient and application of anti-retrovirus therapy, including criteria of selecting medications and their particular combinations. The mathematical strategy had been used to calculate the amount of prospective combinations of anti-retrovirus medications that may be placed on items in some problems. The systemic method had been implemented including content evaluation, types of relative and one-off evaluation, generalization and grouping of data from regulatory documents on anti-retrovirus treatment and official products on anti-retrovirus medications to build up algorithm of logical selection of anti-retrovirus therapy. In line with the results of the research, large number of potential combinations of anti-retrovirus medicines had been set up to select the appropriate combo for treatment of HIV disease. The approach included organizational actions, evaluation criteria and algorithm of picking logical combination of anti-retrovirus medicines. The practical utilization of developed proposals can play a role in improvement system of logical usage of medications in the standard of medical organization and to enhance medication assistance of patients with HIV infection.The incorporated method of diagnosis MI-503 chemical structure and dispensary track of females with high threat for cancer of the breast synthesis of biomarkers , the active recognition of combined pathology of endometrium are promising directions in avoidance and timely diagnosis of breast and womb malignant neoplasms. The study established that particular correction of steps of additional avoidance of cancer of the breast is needed, including formation of risk group and organization of powerful track of females with a high threat of breast cancer development. The extensive study of reproductive system body organs, including evaluation of danger elements, combined usage of mammography and sonography solutions to analyze mammary glands and problem of endometrium, can to boost reliability of differential analysis also to prevent unnecessary unpleasant interventions with mammary glands and early diagnosis of endometrial pathology.The development of the high quality management system is regarded as strategic instructions in healthcare. At the moment, nevertheless, the product quality and protection administration system of health practice in providing palliative medical care is certainly not totally developed. The proposed methodological approaches to growth of the benchmark system specify its application both to certain groups (quality of health care as well as its organization; quality of its construction, procedure and results; hierarchical framework of benchmark system formation) and to such particular specifics of making palliative medical care as non-medical tasks, help family relations of client. The research identified this one regarding the essential criteria needed to be included into tracking may be the estimation of community understanding of possibilities of palliative medical care.