It was mailed to 2,605 households; 1,704 responses were received, yielding a 65.4% response rate. A small incentive (monetary value less than $5) was given if the survey was completed and Dapagliflozin manufacturer returned by August 2008. Youthstyles data were weighted to reflect age and sex of child, household size, household income, head of household age, and race/ethnicity of adult of the US population, as determined by the 2007 Census estimates taken from the Current Population Survey. A traveler to a nonindustrialized country (from now on referred

to as “traveler”) was defined as a respondent who reported traveling in the last 12 months to a destination other than the United States, Canada, Europe, Japan, Australia, or New Zealand. Risk-taking attitude was measured by using a four-item Brief Sensation-Seeking Scale (BSSS-4) derived from the BSSS.8 The four items of the BSSS-4 are designed to assess four previously identified factors that comprise the construct of sensation seeking: experience seeking, disinhibition, thrill and adventure seeking,

and boredom susceptibility. The four items (questions 8–11, Table 1) of the BSSS-4 were scored continuously (1–4), providing a total sensation-seeking score ranging from Talazoparib research buy 4 to 16. Descriptive statistics of frequencies and percentages were analyzed. Fisher’s exact test was used for categorical variables, while Wilcoxon rank-sum test was used for continuous variables. p Values ≤0.05 were considered significant. Bivariate and multivariate logistic regressions were done to calculate odds ratios and 95% confidence intervals for demographic characteristics, with the final multivariate model determined using backwards elimination at a 5% significance level for variable selection. Cronbach’s coefficient alpha Mephenoxalone was used to determine internal consistency reliability for the four subscale survey questions. All analyses were done by using SAS software (Version 9.2; SAS Institute, Cary, NC, USA).

Of the 1,704 respondents, 131 (7.7%) had traveled in the previous 12 months to a nonindustrialized country. The mean age of travelers was 14 years old, and 59% of those who traveled were female (Table 2). Females were more likely to travel than males (p = 0.01). Compared with other variables, travel was also more positively associated with increasing household income (p < 0.0001), marital status of parents (p = 0.007), and increasing household size (p = 0.03). The multivariate model showed that the only significant factors associated with travel were sex (p = 0.01) and household income (p < 0.0001) (Table 2). The regions most often visited were Mexico (44.3%), the Caribbean (42.4%), and Central/South America (12%). The majority traveled for vacation (81.0%), followed by visiting friends or relatives (21.7%) and research/student (5.8%). Nearly one fifth of youth travelers (18.0%) traveled without their parents (Table 3).