In this study, we evaluated the safety and feasibility of the thulium

laser system for ESD. Methods: A total Doxorubicin cost of 10 patients underwent ESD by single expert endoscopist. Adenoma was diagnosed in 5 patients and adenocarcinoma in the remaining five patients. A 2-μm wavelength thulium laser was used for all endoscopic procedures including marking, mucosal incision, submucosal dissection and hemostasis. It was operated in continuous mode with a power setting of 30 to 40 W. A flexible laser fiber, rather than electrosurgical endoknives, was inserted through the working channel of the endoscope. Results: Nine cases were resected en bloc and a piecemeal resection was performed in the remaining case. In one case, the lateral margins showed cancer cell involvement. The median size of resected specimen was 32.5 mm (range 23–63 mm), and the median size of tumor was 12.5 mm (range 9–22 mm). The procedure time was 68.7 ± 50.8 min (mean time ± SD). In five cases, 1–5 immediate see more bleeding events occurred. In other five cases, ESD was completed without immediate bleeding. There were no serious complications during the procedures. Conclusion: The thulium laser system is a safe and feasible method that minimizes immediate bleeding when performing ESD of gastric neoplasia. Key Word(s): 1. gastric neoplasm; 2. thulium laser; Presenting

Author: ZHANG YAOPENG Additional Authors: HUANG YONGHUI Corresponding Author: HUANG YONGHUI Affiliations: Peking University Third medchemexpress Hospital Objective: To

evaluate the clinical application values of different endoscopic therapies in chronic pancreatitis. Methods: The clinical data of 98 cases of chronic pancreatitis in the latest five years diagnosed according to the 2005 guideline were analyzed retrospectively. Endoscopic treatments included endoscopic pancreatic sphincterotomy (EPS), endoscopic papillo-sphincterotomy (EST), pancreatic stenting, pancreatic duct stone extraction, pancreatic duct stricture dilation, biliary duct stenting, naso-pancreatic drainage (ENPD) and naso-biliary drainage (ENBD). The effectiveness and application situation were analyzed. Results: There were 178 endoscopic procedures in 98 cases with 6 times the most and 88.2% successful rate. The longest and average follow-up period was 58 months and 26 months individually. The average period of readmission for endoscopic treatment was 6 months, and the longest was 21 months. In the 98 cases, 86 cases (87.8%) and 30 (30.6%) cases underwent EPS and EST separately, and 6 cases received minor papillo-sphincterotomy. In the 178 procedures, 110 times (61.8%) with major pancreatic duct stenting, 6 times with minor pancreatic duct stenting, 1 times with ENPD, 35 times (19.7%) with pancreatic stone extraction, 23 times (12.9%) with pancreatic duct stricture dilation, 21 times (11.8%) with biliary duct stenting and 3 times with ENBD.