Endoscopic equipment was set up at the health center in Niijima, and skilled endoscopists performed screening using colonoscopy. Endoscopic removal or surgery was indicated
for all detected lesions. The participants were treated at the National Cancer Center Hospital within 6 months after colonoscopy. Results: A total of 656 (39.3%) individuals provided consent for this screening program, and 87.0% (571/656) of participants chose colonoscopy as the primary screening procedure. The participation rate of individuals aged 40–69 years was significantly higher than BAY 57-1293 that of individuals aged 70–79 years (42.4 vs. 29.8%; P < .0001). The completion rate of total colonoscopy was 99.6% (569/571) and there was no complication during this program. Detection rates of invasive cancer, high-grade dysplasia (HGD), advanced neoplasia, and any adenoma were 0.52% (n = 3), 2.6% (n = 15), 12.1% (n = 70), and 50.0% (n = 289), respectively. The adenoma detection rate in men and women aged 40–49 years, 50–59 years, 60–69 years, and 70–79 years was 42.2% and 26.3%, 65.3% and 28.0%, 68.7% and 43.8%, and 73.3% and 50.0%, respectively. The adenoma detection rate and incidence Erastin research buy of advanced neoplasia were significantly
higher in men than in women in all age groups; however, there was no difference in the incidence of HGD and invasive cancer between men and women. Conclusion: The CRC screening program using colonoscopy that was conducted on an island achieved considerably higher participation rate than the conventional screening program using FIT. Completion rate and safety of screening colonoscopy were excellent during http://www.selleck.co.jp/products/Paclitaxel(Taxol).html this program. Detection rates of advanced neoplasia and any adenoma by skilled endoscopists in this program were considerably higher than those of previous reports. Key Word(s): 1. colon cancer screening; 2. colonoscopy; 3. adenoma detection rate Presenting Author: MITSUKO INUYAMA Additional Authors: AI FUJIMOTO, YOSHINORI IGARASHI Corresponding Author: MITSUKO INUYAMA Affiliations: Toho University Omori Medical Center, Toho University Omori Medical Center Objective: Many patients with
colonic diverticular bleeding experience recurrent bleeds within short periods, even when the site of the bleeding is detected and we performed endoscopic hemostasis with clipping. In this study we found the therapeutic barium enema to be effective for colonic diverticular rebleeding within 7 days after administration for lower gastrointestinal endoscopy. Methods: We retrospectively analyzed 219 cases of colonic diverticular bleeding treated between 2003 and 2011. Lower gastrointestinal endoscopy was performed immediately after admission in all cases. Some of these patients received a therapeutic barium enema with 600 ml of 60 w/v percentage barium in addition to conventional therapy. Results: The site of bleeding was identified in 138 (63%) of the 219 patients, and all of these patients underwent endoscopic hemostasis with clipping.